Yitian Chen

📧[email protected]|📞+86 182 2128 1626 / 85251623451|📍FLAT D 4/F CHEUNG HING MANSION NO.2 CHIK SAU LANE SHATIN, NT, HONG KONG

Experience

Hong Kong Polytechnic University

2025-05 – Present

Research Associate

  1. Managed laboratory reagent procurement and reimbursement processes.

  2. Investigated the role of HMGB1 in mechanisms of drug resistance in hepatocellular carcinoma.

Shanghai Jiao Tong University

2024-06 – 2025-04

Postdoctoral

  1. Mainly using animal model to elucidate the precise mechanisms regulating intermediate AT2 cells biology and accumulation in lung fibrosis (IPF, AE-IPF).

  2. Investigating the therapeutic potential of intermediate AT2 cells, which is the stem-like cells in lung regeneration.

  3. Leverage spatial transcriptomes, mIHC (TSA) experiment to generate a spatial niche involved the crosstalk between AT2 and immune microenvironment.

  4. Performed in vivo lineage tracing of targeted fibroblast and co-cultured it with AT2 to support proposal in vitro and vivo.

University of Macau

2023-08 – 2024-05

RA in the FHS

  1. Applied IMC to help Chongqing Daping Hospital to investigate the reason of drug resistance in colon cancer "Spatiotemporal determinants of response to neoadjuvant radiotherapy and immunochemotherapy in locally advanced mismatch repair proficient rectal cancer (TRIUNITE-01):a phase 2 trial".

  2. Tested lung cancer FFPE slides using different mIHC methods, like MACSima platform (cooperated with University of Hong Kong) and Akoya PhenoImager Fusion.

  3. Assist fund declaration: FDCT-MOST (with Shanghai Jiaotong University), NSFC-FDCT (with Hunan University) and FDCT.

  4. Laboratory instruments and reagents management.

University of Macau

2018-12 – 2019-09

RA in the FHS

Worked as a Research Assistant in the Faculty of Health Sciences.

Shanghai Long Hua Hospital

2015-07 – 2017-05

Clinical laboratory technician

Conducted medical experiments in biological immunology and microbiology departments, clinical laboratory and blood transfusion department.

Shanghai Ninth People’s Hospital

2015-01 – 2015-06

Clinical laboratory technician

Completion of graduation thesis with the supervision of Lily Gu. Support in clinical experiments and results analysis.

Languages

Mandarin Native
English Fluent, IELTS Band 6.5

Education

PhD – Biomedical Science

University of Macau

2019-09 – 2023-07

MSc – Chronic Disease and Immunity

University of Leicester

2017-09 – 2019-01 · CGPA: Distinction

BSc – Medical Laboratory Tests and Analysis

Shanghai Jiao Tong University

2011-09 – 2015-06

技能

  • Imaging mass cytometry
  • RIME
  • ChIP-seq
  • Single cell cloning
  • Genomic editing
  • Animal model
  • mIHC

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